Fore-arm rhabdomyosarcoma in neurofibromatosis type 1: A unique case

Rhabdomyosarcoma (RMS) is the commonest soft sarcoma in kids, with alveolar and embryonal variants distinguishable by histopathology and, more significantly, molecular biology. RMS occurs intermittently a substantial proportion of cases without predisposing condition. Nevertheless, it well established that certain hereditary factors enhance likelihood developing RMS. Beckwith–Wiedemann syndrome, Gorlin Costello, NF1, Li Fraumeni syndromes are some them. These present during childhood. A 47-year-old female NF 1 discovered lump her right forearm one year prior to presentation. When patient noticed ulceration on swelling, she sought medical attention. tumor was detected center via MRI, suspected be cystic or myxoid soft-tissue tumor, rhabdomyosarcoma peripheral neural tumor. We classified as stage 4 due axillary lymph node involvement lung metastasis. Histopathology confirmed rhabdomyosarcoma. The then received radiotherapy chemotherapy, went into remission. After confirming NF1 we advise patients adhere standard cancer screening protocol. would assist earlier diagnosis tumors, leading reduction complications.